Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/13229
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Full metadata record
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dc.contributor.author | Powell, B. | - |
dc.contributor.author | Arthur, J. | - |
dc.contributor.author | Nesci, A. | - |
dc.date.issued | 1995 | - |
dc.identifier.citation | Differentiation, 1995; 58(3):227-232 | - |
dc.identifier.issn | 0301-4681 | - |
dc.identifier.issn | 1432-0436 | - |
dc.identifier.uri | http://hdl.handle.net/2440/13229 | - |
dc.description | Copyright © 1999-2009 John Wiley & Sons, Inc. All Rights Reserved. | - |
dc.description.abstract | Many different cysteine-rich proteins are synthesized during hair follicle differentiation, forming part of the interstitial matrix between bundles of intermediate filaments. We have isolated a rabbit gene (rKAP4L¹), a member of a multi gene family that encodes a small cysteine-rich hair keratin associated protein. This is the first complete gene sequence for this family. The rKAP4L gene is expressed in the cortex of rabbit pelage hair follicles at a late stage of hair follicle differentiation, well after the synthesis of the other major hair proteins, the intermediate filament and glycine/tyrosine-rich keratin associated proteins, has commenced. The protein contains 36 mol % cysteine, with a molecular size of 13593 daltons, and its sequence appears to be based on a pentapeptide repeat. It is predicted to adopt a folded conformation characterized by β-turns interspersed with short stretches of β-sheet or random coil | - |
dc.language.iso | en | - |
dc.publisher | Springer-Verlag | - |
dc.source.uri | http://www3.interscience.wiley.com/journal/119247207/abstract | - |
dc.subject | Hair | - |
dc.subject | Animals | - |
dc.subject | Sheep | - |
dc.subject | Rabbits | - |
dc.subject | Cysteine | - |
dc.subject | Proteins | - |
dc.subject | In Situ Hybridization | - |
dc.subject | Chromosome Mapping | - |
dc.subject | Cell Differentiation | - |
dc.subject | Gene Expression | - |
dc.subject | Amino Acid Sequence | - |
dc.subject | Base Sequence | - |
dc.subject | Sequence Homology, Amino Acid | - |
dc.subject | Sequence Homology, Nucleic Acid | - |
dc.subject | Multigene Family | - |
dc.subject | Molecular Sequence Data | - |
dc.subject | Keratins | - |
dc.title | Characterization of a gene encoding a cysteine-rich keratin associated protein synthesized late in rabbit hair follicle differentiation | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1046/j.1432-0436.1995.5830227.x | - |
pubs.publication-status | Published | - |
Appears in Collections: | Agriculture, Food and Wine publications Aurora harvest 7 |
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