Adelaide Research & Scholarship
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https://hdl.handle.net/2440/9789
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| Type: | Journal article |
| Title: | Association of aortic stenosis with platelet hyperaggregability and impaired responsiveness to nitric oxide |
| Author: | Chirkov, Y. Holmes, A. Willoughby, S. Stewart, S. Horowitz, J. |
| Citation: | American Journal of Cardiology, 2002; 90(5):551-554 |
| Publisher: | Excerpta Medica Inc |
| Issue Date: | 2002 |
| ISSN: | 0002-9149 1879-1913 |
| Statement of Responsibility: | Yuliy Y. Chirkov, Andrew S. Holmes, Scott R. Willoughby, Simon Stewart, and John D. Horowitz |
| Abstract: | In summary, the present study demonstrates that AS, irrespective of the presence and/or absence of CAD, is associated with platelet hyperaggregability and hyporesponsiveness to antiaggregatory effects of NO donor SNP. Treatment with the prophylactic antianginal agent perhexiline improves platelet responsiveness to NO. |
| Keywords: | Humans Aortic Valve Stenosis Nitroprusside Nitric Oxide Aspirin Perhexiline Adenosine Diphosphate Cardiovascular Agents Platelet Aggregation Inhibitors Stroke Volume Severity of Illness Index Follow-Up Studies Platelet Aggregation Ventricular Function, Left Adult Aged Aged, 80 and over Middle Aged Female Male Coronary Artery Disease Statistics as Topic |
| Description: | Copyright © 2002 Excerpta Medica Inc. All rights reserved. |
| DOI: | 10.1016/S0002-9149(02)02536-5 |
| Published version: | http://dx.doi.org/10.1016/s0002-9149(02)02536-5 |
| Appears in Collections: | Aurora harvest 4 Medicine publications |
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