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https://hdl.handle.net/2440/9404
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Type: | Journal article |
Title: | Predictors of delayed gastric emptying in diabetes |
Author: | Jones, K. Russo, A. Stevens, J. Wishart, J. Berry, M. Horowitz, M. |
Citation: | Diabetes Care, 2001; 24(7):1264-1269 |
Publisher: | Amer Diabetes Assoc |
Issue Date: | 2001 |
ISSN: | 0149-5992 1935-5548 |
Statement of Responsibility: | Karen L. Jones, Antonietta Russo, Julie E. Stevens, Judith M. Wishart, Melanie K. Berry And Michael Horowitz. |
Abstract: | Objective — To define the predictors of the rate of gastric emptying in patients with diabetes. Research design and methods — A total of 101 outpatients with diabetes (79 type 1 and 22 type 2) underwent measurements of gastric emptying of a solid/liquid meal (scintigraphy), upper gastrointestinal symptoms (questionnaire), glycemic control (blood glucose concentrations during gastric emptying measurement), and autonomic nerve function (cardiovascular reflexes). Results— The gastric emptying of solid and/or liquid was delayed in 66 (65%) patients. Solid (retention at 100 min 64 6 3.2 vs. 50.2 6 3.6%, P , 0.005) and liquid (retention at 100 min 22.761.7 vs. 16.061.8%, P,0.001) gastric emptying was slower in women than in men. Of all upper gastrointestinal symptoms (including nausea and vomiting), only abdominal bloating/ fullness was associated with slower gastric emptying (P , 0.005). A multiple regression analysis demonstrated that both abdominal bloating/fullness and female sex were predictors of slower gastric emptying of both solids and liquids. Conclusions — We conclude that the presence of abdominal bloating/fullness but not any other upper gastrointestinal symptom is associated with diabetic gastroparesis and that gastric emptying is slower in diabetic women than in diabetic men. |
Keywords: | Autonomic Nervous System Animals Cattle Humans Gastrointestinal Diseases Diabetes Mellitus Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Blood Glucose Blood Pressure Heart Rate Systole Gastric Emptying Meat Middle Aged Outpatients Surveys and Questionnaires |
Rights: | Copyright © 2001 American Diabetes Association |
DOI: | 10.2337/diacare.24.7.1264 |
Published version: | http://dx.doi.org/10.2337/diacare.24.7.1264 |
Appears in Collections: | Aurora harvest Medicine publications |
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