Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/87361
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Full metadata record
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dc.contributor.author | Dodd, I.B. | - |
dc.contributor.author | Egan, J.B. | - |
dc.date.issued | 1990 | - |
dc.identifier.citation | Nucleic Acids Research, 1990; 18(17):5019-5026 | - |
dc.identifier.issn | 0305-1048 | - |
dc.identifier.issn | 1362-4962 | - |
dc.identifier.uri | http://hdl.handle.net/2440/87361 | - |
dc.description.abstract | We present an update of our method for systematic detection and evaluation of potential hellx-turn-helix DNA-binding motifs in protein sequences [Dodd, I. and Egan, J. B. (1987) J. Mol. Biol. 194, 557-564]. The new method is considerably more powerful, detecting approximately 50% more likely hellx-turn-helix sequences without an Increase In false predictions. This improvement is due almost entirely to the use of a much larger reference set of 91 presumed helix-tumhellx sequences. The scoring matrix derived from this reference set has been calibrated against a large protein sequence database so that the score obtained by a sequence can be used to give a practical estimation of the probability that the sequence Is a helix-turn-helix motif. | - |
dc.description.statementofresponsibility | Ian B.Dodd and J.Barry Egan | - |
dc.language.iso | en | - |
dc.publisher | Oxford University Press | - |
dc.rights | © 1990 Oxford University Press | - |
dc.source.uri | http://dx.doi.org/10.1093/nar/18.17.5019 | - |
dc.subject | Animals | - |
dc.subject | DNA-Binding Proteins | - |
dc.subject | DNA | - |
dc.subject | Probability | - |
dc.subject | Amino Acid Sequence | - |
dc.subject | Protein Conformation | - |
dc.subject | Molecular Sequence Data | - |
dc.subject | Information Systems | - |
dc.title | Improved detection of helix-turn-helix DNA-binding motifs in protein sequences | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1093/nar/18.17.5019 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Dodd, I.B. [0000-0003-2969-6841] | - |
Appears in Collections: | Aurora harvest 7 Molecular and Biomedical Science publications |
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hdl_87361.pdf | Published version | 763.38 kB | Adobe PDF | View/Open |
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