Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/81644
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dc.contributor.authorPepper, H.-
dc.contributor.authorGeorge, J.-
dc.date.issued2013-
dc.identifier.citationAngewandte Chemie International Edition, 2013; 52(46):12170-12173-
dc.identifier.issn1433-7851-
dc.identifier.issn1521-3773-
dc.identifier.urihttp://hdl.handle.net/2440/81644-
dc.description.abstractInspired: The proposed biosynthetic pathway toward the potent antibiotic meroterpenoid (±)-merochlorinA inspired its concise total synthesis. The key steps in the synthesis are a one-pot aromatization-alkylation reaction, followed by a biomimetic oxidative dearomatization of a highly functionalized naphthalene derivative, which forms two rings and four contiguous stereocenters in a single step. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.-
dc.description.statementofresponsibilityHenry P. Pepper and Jonathan H. George-
dc.language.isoen-
dc.publisherWiley-V C H Verlag GMBH-
dc.rightsCopyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim-
dc.source.urihttp://dx.doi.org/10.1002/anie.201307200-
dc.subjectantibiotics-
dc.subjectbiomimetic synthesis-
dc.subjectcascade reactions-
dc.subjectnatural products-
dc.titleBiomimetic total synthesis of (±)-merochlorin A-
dc.title.alternativeBiomimetic total synthesis of (+)-merochlorin A-
dc.typeJournal article-
dc.identifier.doi10.1002/anie.201307200-
dc.relation.granthttp://purl.org/au-research/grants/arc/DE130100689-
dc.relation.granthttp://purl.org/au-research/grants/arc/DE130100689-
pubs.publication-statusPublished-
dc.identifier.orcidGeorge, J. [0000-0002-7330-2160]-
Appears in Collections:Aurora harvest 4
Chemistry and Physics publications

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