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https://hdl.handle.net/2440/6581
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Type: | Journal article |
Title: | Effects of Clozapine for Non-Treatment-Resistant Patients with Schizophrenia |
Author: | Galletly, C. Clark, C. McFarlane, A. Weber, D. |
Citation: | Psychiatric Services, 1999; 50(1):101-103 |
Publisher: | AMER PSYCHIATRIC PUBLISHING, INC |
Issue Date: | 1999 |
ISSN: | 1075-2730 1557-9700 |
Abstract: | Clozapine is generally used for patients meeting criteria for treatment resistance. In this study clozapine was given to 19 patients with schizophrenia who did not meet these criteria and whose symptoms were mild to moderate in severity. Clozapine was associated with significant improvement in positive and negative symptoms and quality of life. A more modest improvement on a range of tests of cognitive functioning was also noted. These results suggest that consideration should be given to broadening the usual criteria for patients' eligibility for clozapine treatment. |
Keywords: | Humans Clozapine Antipsychotic Agents Treatment Outcome Drug Administration Schedule Schizophrenia Psychiatric Status Rating Scales Dose-Response Relationship, Drug Quality of Life Adult Female Male |
DOI: | 10.1176/ps.50.1.101 |
Published version: | http://dx.doi.org/10.1176/ps.50.1.101 |
Appears in Collections: | Aurora harvest Psychiatry publications |
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