Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/55515
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Combination pharmacotherapy in unipolar depression |
Author: | Ng, F. Dodd, S. Berk, M. |
Citation: | Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders, 2006; 6(7):1049-1060 |
Publisher: | Expert Reviews Ltd. |
Issue Date: | 2006 |
ISSN: | 1473-7175 1744-8360 |
Statement of Responsibility: | Ng, F; Dodd, S and Berk M. |
Abstract: | It is estimated that between 60 and 80% of those with major depressive disorder do not achieve full symptomatic remission from first-line antidepressant monotherapy. Residual depressive symptoms substantially impair quality of life and add to the risk of recurrence. It is now clear that depression would benefit from more vigorous treatment, in order to ameliorate its disease burden. While there are established algorithms in situations of treatment resistance, the use of combination pharmacotherapy in unipolar depression is a relatively under-investigated area of treatment and may be an effective and tolerable strategy that maximizes the available resources. This paper reviews the current evidence for combination pharmacotherapy in unipolar depression and discusses its clinical applications. |
Keywords: | Humans Antipsychotic Agents Antidepressive Agents Drug Combinations Treatment Outcome Drug Therapy Drug Administration Schedule Depressive Disorder Dose-Response Relationship, Drug Drug Synergism Clinical Trials as Topic Practice Guidelines as Topic Practice Patterns, Physicians' |
DOI: | 10.1586/14737175.6.7.1049 |
Description (link): | http://www.ncbi.nlm.nih.gov/pubmed/16831118 |
Published version: | http://dx.doi.org/10.1586/14737175.6.7.1049 |
Appears in Collections: | Aurora harvest 5 Psychiatry publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.