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https://hdl.handle.net/2440/52215
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Type: | Journal article |
Title: | Ten-year clinical outcome of a prospective randomized clinical trial of laparoscopic Nissen versus anterior 180° partial fundoplication |
Other Titles: | Ten-year clinical outcome of a prospective randomized clinical trial of laparoscopic Nissen versus anterior 180degrees partial fundoplication |
Author: | Cai, W. Watson, D. Lally, C. Devitt, P. Game, P. Jamieson, G. |
Citation: | British Journal of Surgery, 2008; 95(12):1501-1505 |
Publisher: | John Wiley & Sons Ltd |
Issue Date: | 2008 |
ISSN: | 0007-1323 1365-2168 |
Statement of Responsibility: | W. Cai, D. I. Watson, C. J. Lally, P. G. Devitt, P. A. Game and G. G. Jamieson |
Abstract: | <h4>Background</h4>A randomized trial of laparoscopic Nissen fundoplication and anterior 180 degrees partial fundoplication was undertaken to determine whether the anterior procedure might reduce the incidence of dysphagia and other adverse outcomes following surgery for gastro-oesophageal reflux disease. This study evaluated clinical outcomes after 10 years.<h4>Methods</h4>Some 107 patients were randomized to undergo laparoscopic Nissen or anterior 180 degrees partial fundoplication. Ten-year data were not available for 18 patients. Information was obtained from 89 patients (48 Nissen, 41 anterior fundoplication) using a standard clinical questionnaire that focused on symptoms of reflux, potential postoperative side-effects and overall satisfaction with the outcome of surgery.<h4>Results</h4>There were no significant differences between the two groups with regard to reflux symptoms, dysphagia, abdominal bloating, ability to belch and overall satisfaction. Between 5 and 10 years after surgery, revisional surgery was required for reflux in two patients after anterior fundoplication. Two patients had revision after Nissen fundoplication, for reflux and recurrent hiatus hernia.<h4>Conclusion</h4>Both laparoscopic anterior 180 degrees partial and Nissen fundoplication are safe, effective and durable at 10 years' follow-up. Most patients are satisfied with the clinical outcome. |
Keywords: | Humans Deglutition Disorders Gastroesophageal Reflux Hernia, Hiatal Recurrence Postoperative Complications Laparoscopy Treatment Outcome Fundoplication Prospective Studies Double-Blind Method Middle Aged Patient Satisfaction |
DOI: | 10.1002/bjs.6318 |
Published version: | http://dx.doi.org/10.1002/bjs.6318 |
Appears in Collections: | Aurora harvest Surgery publications |
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