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https://hdl.handle.net/2440/43079
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Type: | Journal article |
Title: | Retrospective study of survival and treatment pattern in a cohort of patients with oral and oropharyngeal tongue cancers from 1987 to 2004 |
Author: | Lam, L. Logan, R. Luke, C. Rees, G. |
Citation: | Oral Oncology, 2007; 43(2):150-158 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2007 |
ISSN: | 1368-8375 1879-0593 |
Statement of Responsibility: | Lisetta Lam, Richard M. Logan, Colin Luke and Guy L. Rees |
Abstract: | This is a retrospective study of patients with oral and oropharyngeal tongue cancers who presented to the Royal Adelaide Hospital (RAH) from 1987 to 2004. The aims of this study were to determine sociodemographic and tumour characteristics, treatment patterns and five-year disease-specific survival of the disease. All cases of tongue cancers, including untreated and palliative cases, were identified through the Royal Adelaide Hospital Cancer Registry and were included in statistical analysis. A total of 212 cases of tongue cancer were identified. Patients less than 45 years of age accounted for 15% of cases and had a tendency to present with advanced stage disease. Squamous cell carcinoma was the most common histological type. Almost 30% of recorded cases were oropharyngeal or base of tongue cancers. Nearly half of the patients had advanced stage (III and IV) disease at presentation, which was significantly associated with rural area of residence, base of tongue sub-site and early diagnostic period. Treatment involved a multidisciplinary approach and majority of patients were treated with a curative intent. Palliative treatment was more likely to be given to patient with oropharyngeal tongue cancers or advance stage disease. There was no significant improvement of five-year disease-specific survival over the 18-year period. Poorer survival was significantly associated with age 45 years or older, oropharyngeal tongue cancers and advanced stage disease. Tongue cancer is an important health issue associated with poor survival. Early detection and diagnosis is important in order to improve survival rate for this malignancy. |
Keywords: | Humans Carcinoma, Squamous Cell Tongue Neoplasms Oropharyngeal Neoplasms Neoplasm Staging Prognosis Treatment Outcome Combined Modality Therapy Palliative Care Epidemiologic Methods Adult Aged Middle Aged Female Male |
Description: | Copyright © 2006 Elsevier Ltd All rights reserved. |
DOI: | 10.1016/j.oraloncology.2005.12.030 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/105/description#description |
Published version: | http://dx.doi.org/10.1016/j.oraloncology.2005.12.030 |
Appears in Collections: | Aurora harvest 6 Dentistry publications |
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