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https://hdl.handle.net/2440/39011
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dc.contributor.author | Sacher, F. | - |
dc.contributor.author | Monahan, K. | - |
dc.contributor.author | Thomas, S. | - |
dc.contributor.author | Davidson, N. | - |
dc.contributor.author | Adragao, P. | - |
dc.contributor.author | Sanders, P. | - |
dc.contributor.author | Hocini, M. | - |
dc.contributor.author | Takahashi, Y. | - |
dc.contributor.author | Rotter, M. | - |
dc.contributor.author | Rostock, T. | - |
dc.contributor.author | Hsu, L. | - |
dc.contributor.author | Clementy, J. | - |
dc.contributor.author | Haissaguerre, M. | - |
dc.contributor.author | Ross, D. | - |
dc.contributor.author | Packer, D. | - |
dc.contributor.author | Jais, P. | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Journal of the American College of Cardiology, 2006; 47(12):2498-2503 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.issn | 1558-3597 | - |
dc.identifier.uri | http://hdl.handle.net/2440/39011 | - |
dc.description | © 2006 American College of Cardiology Foundation | - |
dc.description.abstract | <h4>Objectives</h4>The purpose of this study was to characterize the occurrence of phrenic nerve injury (PNI) and its outcome after radiofrequency (RF) ablation of atrial fibrillation (AF).<h4>Background</h4>It is recognized that extra-myocardial damage may develop owing to penetration of ablative energy.<h4>Methods</h4>Between 1997 and 2004, 3,755 consecutive patients underwent AF ablation at five centers. Among them, 18 patients (0.48%; 9 male, 54 +/- 10 years) had PNI (16 right, 2 left). The procedure consisted of pulmonary vein (PV) isolation in 15 patients and anatomic circumferential ablation in 3 patients, with additional left atrial lesions (n = 11) and/or superior vena cava (SVC) disconnection (n = 4).<h4>Results</h4>Right PNI occurred during ablation of right superior PV (n = 12) or SVC disconnection (n = 3). Left PNI occurred during ablation at the left atrial appendage. Immediate features were dyspnea, cough, hiccup, and/or sudden diaphragmatic elevation in 9, and in the remaining the diagnosis was made after ablation owing to dyspnea (n = 7) or on routine radiographic evaluation (n = 2). Four patients (22%) were asymptomatic. Complete recovery occurred in 12 patients (66%). Recovery occurred within 24 h in the two patients with left PNI and in one patient with right PNI occurring with SVC disconnection. In the other nine patients, right PNI recovery occurred after 4 +/- 5 months (1 to 12 months) with respiratory rehabilitation. After a mean follow-up of 36 +/- 33 months, six patients have persistent PNI (three with partial and three with no recovery).<h4>Conclusions</h4>In this multicenter experience, PNI was a rare complication (0.48%) of AF ablation. Ablation of the right superior PV, SVC, and left atrial appendage were associated with PNI. Complete (66%) or partial (17%) recovery was observed in the majority. | - |
dc.description.statementofresponsibility | Frédéric Sacher, Kristi H. Monahan, Stuart P. Thomas, Neil Davidson, Pedro Adragao, Prashanthan Sanders, Mélèze Hocini, Yoshihide Takahashi, Martin Rotter, Thomas Rostock, Li-Fern Hsu, Jacques Clémenty, Michel Haïssaguerre, David L. Ross, Douglas L. Packer, Pierre Jaïs | - |
dc.language.iso | en | - |
dc.publisher | Elsevier Science Inc | - |
dc.source.uri | http://dx.doi.org/10.1016/j.jacc.2006.02.050 | - |
dc.subject | Phrenic Nerve | - |
dc.subject | Humans | - |
dc.subject | Atrial Fibrillation | - |
dc.subject | Intraoperative Complications | - |
dc.subject | Catheter Ablation | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.title | Phrenic nerve injury after atrial fibrillation catheter ablation: characterization and outcome in a multicenter study | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.jacc.2006.02.050 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Sanders, P. [0000-0003-3803-8429] | - |
Appears in Collections: | Aurora harvest Medicine publications |
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