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https://hdl.handle.net/2440/23474
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Type: | Journal article |
Title: | Measurements of gastric emptying of low- and high-nutrient liquids using 3D ultrasonography and scintigraphy in healthy subjects |
Author: | Gentilcore, D. Hausken, T. Horowitz, M. Jones, K. |
Citation: | Neurogastroenterology and Motility, 2006; 18(12):1062-1068 |
Publisher: | Blackwell Publishing Ltd |
Issue Date: | 2006 |
ISSN: | 1350-1925 1365-2982 |
Statement of Responsibility: | D. Gentilcore, T. Hausken, M. Horowitz & K. L. Jones |
Abstract: | Scintigraphy represents the 'gold standard' for the measurement of gastric emptying. Recent studies suggest that three-dimensional (3D) ultrasonography may allow a precise measure of gastric emptying, given the capacity for accurate volume calculations of the stomach. The aim of this study was to compare measurements of gastric emptying of both low- and high-nutrient drinks by 3D ultrasonography with scintigraphy. Ten healthy young subjects (6M, 4F, age 23.5 ± 1.5 years) were studied on 2 days. Concurrent measurements of gastric emptying by scintigraphy and 3D ultrasonography were performed after ingestion of 500 mL beef soup (12 kcal) or 300 ml dextrose (25% w/v) (314 kcal) labelled with 20 MBq 99mTc-sulphur colloid. There was no significant difference between scintigraphic and ultrasonographic 50% emptying times (T50s) (soup: 27.7 ± 4.8 min vs 23.8. ± 4.8 min; dextrose: 122.2 ± 13.3 min vs 131.9 ± 10.2 min). There was a close correlation between scintigraphic and ultrasonographic T50s for both soup (r ¼ 0.92, P ¼ 0.0005) and dextrose (r ¼ 0.88, P ¼ 0.0007). For the T50s, the limits of agreement were )15.2 min and +8.1 min for the soup (mean difference)3.6 min) and )35.3 min and +47.6 min for dextrose (mean difference +6.2 min). 3D ultrasonography provides a valid measure of gastric emptying of liquid meals in healthy subjects. |
Keywords: | real-time ultrasound 3-dimensional ultrasonography functional dyspepsia intragastric distribution antroduodenal motility nonulcer dyspepsia transpyloric flow volume estimation proximal stomach in-vivo |
Description: | The definitive version is available at www.blackwell-synergy.com |
DOI: | 10.1111/j.1365-2982.2006.00830.x |
Published version: | http://dx.doi.org/10.1111/j.1365-2982.2006.00830.x |
Appears in Collections: | Aurora harvest 6 Medicine publications |
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