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https://hdl.handle.net/2440/23231
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Type: | Journal article |
Title: | RANK expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone |
Author: | Atkins, G. Kostakis, P. Vincent, C. Farrugia, A. Houchins, J. Findlay, D. Evdokiou, A. Zannettino, A. |
Citation: | Journal of Bone and Mineral Research, 2006; 21(9):1339-1349 |
Publisher: | Amer Soc Bone & Mineral Res |
Issue Date: | 2006 |
ISSN: | 0884-0431 1523-4681 |
Statement of Responsibility: | Gerald J Atkins, Panagiota Kostakis, Cristina Vincent, Amanda N Farrugia, Jeffrey P Houchins, David M Findlay, Andreas Evdokiou, and Andrew CW Zannettino |
Abstract: | RANK expression in vivo on hematopoietic subsets including pre-osteoclasts, identified by monoclonal antibodies, has not been described. We describe the lineages that express RANK in bone marrow, peripheral blood, and GCTs. We show that CD14+RANKhigh cells constitute a circulating pre-osteoclast pool. |
Keywords: | RANK hematopoietic cells giant cell tumor monoclonal antibodies |
Description: | © 2006 American Society for Bone and Mineral Research |
DOI: | 10.1359/jbmr.060604 |
Published version: | http://www.jbmronline.org/doi/abs/10.1359/jbmr.060604 |
Appears in Collections: | Aurora harvest 6 Orthopaedics and Trauma publications |
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