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Type: Journal article
Title: RANK expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone
Author: Atkins, G.
Kostakis, P.
Vincent, C.
Farrugia, A.
Houchins, J.
Findlay, D.
Evdokiou, A.
Zannettino, A.
Citation: Journal of Bone and Mineral Research, 2006; 21(9):1339-1349
Publisher: Amer Soc Bone & Mineral Res
Issue Date: 2006
ISSN: 0884-0431
Statement of
Gerald J Atkins, Panagiota Kostakis, Cristina Vincent, Amanda N Farrugia, Jeffrey P Houchins, David M Findlay, Andreas Evdokiou, and Andrew CW Zannettino
Abstract: RANK expression in vivo on hematopoietic subsets including pre-osteoclasts, identified by monoclonal antibodies, has not been described. We describe the lineages that express RANK in bone marrow, peripheral blood, and GCTs. We show that CD14+RANKhigh cells constitute a circulating pre-osteoclast pool.
Keywords: RANK
hematopoietic cells
giant cell tumor
monoclonal antibodies
Description: © 2006 American Society for Bone and Mineral Research
DOI: 10.1359/jbmr.060604
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Appears in Collections:Aurora harvest 6
Orthopaedics and Trauma publications

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