Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/14282
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Berry, M. | - |
dc.contributor.author | Russo, A. | - |
dc.contributor.author | Wishart, J. | - |
dc.contributor.author | Tonkin, A. | - |
dc.contributor.author | Horowitz, M. | - |
dc.contributor.author | Jones, K. | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | American Journal of Physiology: Gastrointestinal and Liver Physiology, 2003; 284(4):G655-G662 | - |
dc.identifier.issn | 0193-1857 | - |
dc.identifier.issn | 1522-1547 | - |
dc.identifier.uri | http://hdl.handle.net/2440/14282 | - |
dc.description | Published abstract used with permission of the copyright owner. | - |
dc.description.abstract | Gastric emptying is a determinant of the postprandial glycemic and cardiovascular responses to oral carbohydrate. We evaluated the effects of a solid meal on gastric emptying and the glycemic and cardiovascular responses to oral glucose in healthy older subjects. Ten subjects aged 72.1 ± 1.9 yr were studied. Each subject had measurements of gastric emptying, blood glucose, serum insulin, blood pressure, and heart rate after ingestion of a 50-g glucose drink (300 ml) with (mixed meal) or without (liquid only) a solid meal (300 g ground beef). Gastric emptying of liquid was initially slightly more rapid (P < 0.05) after the mixed meal compared with liquid only at 5 min (92.0 ± 1.5 vs. 96.0 ± 1.3%) and much slower (P < 0.05) after 120 min. The time to peak blood glucose was less (39.0 ± 4.0 vs. 67.5 ± 10.3 min; P < 0.01) and blood glucose subsequently lower (P < 0.01) after the mixed meal. The increase in serum insulin was greater (P < 0.001) after the mixed meal. Blood pressure fell (P < 0.05) in the first 30 min, with no difference between the two meals. Increase in heart rate after both meals (P < 0.005), was greater (P < 0.05) after the mixed meal. The presence of a noncarbohydrate solid meal had discrepant effects on early and subsequent emptying of a nutrient liquid, which affects postprandial glycemia and increased heart rate. | - |
dc.description.statementofresponsibility | Melanie K. Berry, Antonietta Russo, Judith M. Wishart, Anne Tonkin, Michael Horowitz, and Karen L. Jones | - |
dc.language.iso | en | - |
dc.publisher | Amer Physiological Soc | - |
dc.rights | Copyright © 2005 by the American Physiological Society | - |
dc.source.uri | http://dx.doi.org/10.1152/ajpgi.00163.2002 | - |
dc.subject | glycemic control | - |
dc.subject | blood pressure | - |
dc.subject | postprandial hypotension | - |
dc.subject | blood glucose | - |
dc.title | Effect of solid meal on gastric emptying of, and glycemic and cardiovascular responses to, liquid glucose in older subjects | - |
dc.type | Journal article | - |
dc.contributor.organisation | Medicine Learning and Teaching Unit | - |
dc.identifier.doi | 10.1152/ajpgi.00163.2002 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Horowitz, M. [0000-0002-0942-0306] | - |
dc.identifier.orcid | Jones, K. [0000-0002-1155-5816] | - |
Appears in Collections: | Aurora harvest 2 Pharmacology publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.