Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/133122
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Type: | Journal article |
Title: | Health-related quality of life among patients with comorbid diabetes and kidney disease attending a codesigned integrated model of care: a longitudinal study |
Author: | Zimbudzi, E. Lo, C. Ranasinha, S. Teede, H. Usherwood, T. Polkinghorne, K.R. Fulcher, G. Gallagher, M. Jan, S. Cass, A. Walker, R. Russell, G. Johnson, G. Kerr, P.G. Zoungas, S. |
Citation: | BMJ Open Diabetes Research & Care, 2020; 8(1):1-8 |
Publisher: | BMJ |
Issue Date: | 2020 |
ISSN: | 2052-4897 2052-4897 |
Statement of Responsibility: | Edward Zimbudzi, Clement Lo, Sanjeeva Ranasinha, Helena Teede, Tim Usherwood, Kevan R Polkinghorne ... et al. |
Abstract: | OBJECTIVE:To evaluate the impact of an integrated diabetes and kidney disease model of care on health-related quality of life (HRQOL) of patients with comorbid diabetes and chronic kidney disease (CKD). RESEARCH DESIGN AND METHODS:A longitudinal study of adult patients (over 18 years) with comorbid diabetes and CKD (stage 3a or worse) who attended a new diabetes kidney disease service was conducted at a tertiary hospital. A questionnaire consisting of demographics, clinical data, and the Kidney Disease Quality of Life (KDQOL-36) was administered at baseline and after 12 months. Paired t-tests were used to compare baseline and 12-month scores. A subgroup analysis examined the effects by patient gender. Multiple regression analysis examined the factors associated with changes in scores. RESULTS:179 patients, 36% of whom were female, with baseline mean±SD age of 65.9±11.3 years, were studied. Across all subscales, HRQOL did not significantly change over time (p value for all mean differences >0.05). However, on subgroup analysis, symptom problem list and physical composite summary scores increased among women (MD=9.0, 95% CI 1.25 to 16.67; p=0.02 and MD=4.5, 95% CI 0.57 to 8.42; p=0.03 respectively) and physical composite scores decreased among men (MD=-3.35, 95% CI -6.26 to -0.44; p=0.03). CONCLUSION:The HRQOL of patients with comorbid diabetes and CKD attending a new codesigned, integrated diabetes and kidney disease model of care was maintained over 12 months. Given that HRQOL is known to deteriorate over time in this high-risk population, the impact of these findings on clinical outcomes warrants further investigation. |
Keywords: | chronic kidney disease quality of Life type 2 diabetes |
Rights: | © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ |
DOI: | 10.1136/bmjdrc-2019-000842 |
Published version: | http://dx.doi.org/10.1136/bmjdrc-2019-000842 |
Appears in Collections: | Medicine publications |
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hdl_133122.pdf | Published version | 397.44 kB | Adobe PDF | View/Open |
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