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https://hdl.handle.net/2440/132497
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Type: | Journal article |
Title: | Diverse particle carriers prepared by co-precipitation and phase separation: formation and applications |
Author: | Sun, Z. Wu, B. Ren, Y. Wang, Z. Zhao, C.X. Hai, M. Weitz, D.A. Chen, D. |
Citation: | ChemPlusChem, 2021; 86(1):49-58 |
Publisher: | Wiley |
Issue Date: | 2021 |
ISSN: | 2192-6506 2192-6506 |
Statement of Responsibility: | Zhu Sun, Baiheng Wu, Yixin Ren, Zhongzhen Wang, Chun-Xia Zhao, Mingtan Hai |
Abstract: | Nanoparticles with diverse structures and unique properties have attracted increasing attention for their widespread applications. Co-precipitation under rapid mixing is an effective method to obtained biocompatible nanoparticles and diverse particle carriers are achieved by controlled phase separation via interfacial tensions. In this Minireview, we summarize the underlying mechanism of co-precipitation and show that rapid mixing is important to ensure co-precipitation. In the binary polymer system, the particles can form four different morphologies, including occluded particle, core-shell capsule, dimer particle, and heteroaggregate, and we demonstrate that the final morphology could be controlled by surface tensions through surfactant, polymer composition, molecular weight, and temperature. The applications of occluded particles, core-shell capsules and dimer particles prepared by co-precipitation or microfluidics upon the regulation of interfacial tensions are discussed in detail, and show great potential in the areas of functional materials, colloidal surfactants, drug delivery, nanomedicine, bio-imaging, displays, and cargo encapsulation. |
Keywords: | cargo delivery interfacial tension microfluidics nanostructures precipitation |
Rights: | © 2020 Wiley-VCH GmbH. |
DOI: | 10.1002/cplu.202000497 |
Grant ID: | http://purl.org/au-research/grants/arc/FT140100726 |
Published version: | http://dx.doi.org/10.1002/cplu.202000497 |
Appears in Collections: | Chemistry publications |
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