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https://hdl.handle.net/2440/120574
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dc.contributor.author | Olsson, L.G. | - |
dc.contributor.author | Swedberg, K. | - |
dc.contributor.author | Lappas, G. | - |
dc.contributor.author | Stewart, S. | - |
dc.contributor.author | Rosengren, A. | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | International Journal of Cardiology, 2013; 167(3):733-738 | - |
dc.identifier.issn | 0167-5273 | - |
dc.identifier.issn | 1874-1754 | - |
dc.identifier.uri | http://hdl.handle.net/2440/120574 | - |
dc.description.abstract | Background: To investigate recent trends in incidence of hemorrhagic and non-hemorrhagic strokes in patients with atrial fibrillation (AF). Methods: The Swedish Hospital Discharge and Cause of Death Registries were linked to provide outcome data. Results: 321,276 patients 35 to 84 years (56.5% male, mean age 71.5 years) free of prior stroke with a first AF diagnosis during 1987-2006 were included. Over 3 year follow-up 24,733 patients (7.7%) were diagnosed with ischemic stroke and 2292 (0.7%) with hemorrhagic stroke. The 3-year incidence of ischemic stroke decreased from 8.7% for patients diagnosed in 1987-1991 to 6.6% for those diagnosed in 2002 to 2006. The corresponding incidence of hemorrhagic stroke increased from 0.38% for patients diagnosed in 1987-1991 to 0.57% for those diagnosed in 2002 to 2006. Covariable-adjusted risk of ischemic stroke was significantly reduced (HR 0.65; 0.63-0.68) while risk of hemorrhagic stroke was significantly increased (HR 1.19; 1.05-1.36). Compared to the general population, total stroke risk decreased more among AF patients. Conclusion: We found a considerable decrease in risk of ischemic stroke in Sweden in patients without prior stroke and with a first hospital diagnosis of AF. There was an increased risk of hemorrhagic stroke, but because hemorrhagic stroke represented only a small proportion of all strokes, the overall risk of stroke declined. | - |
dc.description.statementofresponsibility | Lars G. Olsson, Karl Swedberg, Georg Lappas, Simon Stewart, Annika Rosengren | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.rights | © 2012 Elsevier Ireland Ltd. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.ijcard.2012.03.057 | - |
dc.subject | Atrial fibrillation; acute stroke; epidemiology; prevention | - |
dc.title | Trends in stroke incidence after hospitalization for atrial fibrillation in Sweden 1987 to 2006 | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.ijcard.2012.03.057 | - |
dc.relation.grant | NHMRC | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Stewart, S. [0000-0001-9032-8998] | - |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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