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https://hdl.handle.net/2440/114988
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Type: | Journal article |
Title: | An empirical comparison of the EQ-5D-5L, DEMQOL-U and DEMQOL-Proxy-U in a post-hospitalisation population of frail older people living in residential aged care |
Author: | Ratcliffe, J. Flint, T. Easton, T. Killington, M. Cameron, I. Davies, O. Whitehead, C. Kurrle, S. Miller, M. Liu, E. Crotty, M. |
Citation: | Applied Health Economics and Health Policy, 2017; 15(3):399-412 |
Publisher: | Springer International Publishing |
Issue Date: | 2017 |
ISSN: | 1175-5652 1179-1896 |
Statement of Responsibility: | Julie Ratcliffe, Thomas Flint, Tiffany Easton, Maggie Killington, Ian Cameron, Owen Davies, Craig Whitehead, Susan Kurrle, Michelle Miller, Enwu Liu, Maria Crotty |
Abstract: | Objective: To empirically compare the measurement properties of the DEMQOL-U and DEMQOL-Proxy-U instruments to the EQ-5D-5L and its proxy version (CEQ-5D-5L) in a population of frail older people living in residential aged care in the post-hospitalisation period following a hip fracture. Methods: A battery of instruments to measure health-related quality of life (HRQoL), cognition, and clinical indicators of depression, pain and functioning were administered at baseline and repeated at 4 weeks’ follow-up. Descriptive summary statistics were produced and psychometric analyses were conducted to assess the levels of agreement, convergent validity and known group validity between clinical indicators and HRQoL measures. Results: There was a large divergence in mean (SD) utility scores at baseline for the EQ-5D-5L and DEMQOL-U [EQ-5D-5L mean 0.21 (0.19); DEMQOL-U mean 0.79 (0.14)]. At 4 weeks’ follow-up, there was a marked improvement in EQ-5D-5L scores whereas DEMQOL-U scores had deteriorated. [EQ-5D-5L mean 0.45 (0.38); DEMQOL-U mean 0.58 (0.38)]. The EQ-5D and CEQ-5D-5L were more responsive to the physical recovery trajectory experienced by frail older people following surgery to repair a fractured hip, whereas the DEMQOL-U and DEMQOL-Proxy-U appeared more responsive to the changes in delirium and dementia symptoms often experienced by frail older people in this period. Conclusions: This study presents important insights into the HRQoL of a relatively under-researched population of post-hospitalisation frail older people in residential care. Further research should investigate the implications for economic evaluation of self-complete versus proxy assessment of HRQoL and the choice of preference-based instrument for the measurement and valuation of HRQoL in older people exhibiting cognitive decline, dementia and other co-morbidities. |
Keywords: | Hip Fractures |
Description: | Published online: 23 November 2016 |
Rights: | © Springer International Publishing Switzerland 2016 |
DOI: | 10.1007/s40258-016-0293-7 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/9100000 |
Published version: | http://dx.doi.org/10.1007/s40258-016-0293-7 |
Appears in Collections: | Aurora harvest 8 Public Health publications |
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