Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/113890
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | In vitro biocompatibility of a nanocrystalline β-Ta₂O₅ coating for orthopaedic implants |
Other Titles: | In vitro biocompatibility of a nanocrystalline beta-Ta(2)O(5) coating for orthopaedic implants |
Author: | Xu, J. Bao, X. Fu, T. Lyu, Y. Munroe, P. Xie, Z. |
Citation: | Ceramics International, 2018; 44(5):4660-4675 |
Publisher: | Elsevier |
Issue Date: | 2018 |
ISSN: | 0272-8842 1873-3956 |
Statement of Responsibility: | Jiang Xua, Xi ke Bao, Tao Fu, Yinghai Lyu, Paul Munroe, Zong-Han Xie |
Abstract: | To improve the durability and bioactivity of Ti–6Al–4V alloy used for medical implants, the β-Ta2O5 nano-crystalline coatings were introduced using double cathode glow discharge technique. The coating microstructure was characterized using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and high-resolution transmission electron microscopy (HRTEM). The coating exhibits an assembly of near-equiaxed grains, locally aligned normal to the coating surface. The β-Ta2O5 coating exhibits strong adhesion to substrate and a strong resistance to deformation and cracking under applied loads. Cells culture tests showed that the coating is more beneficial to the adhesion and proliferation of NIH-3T3 cells as compared to the uncoated alloy. In-vitro bioactivity was evaluated by immersion of the coating in simulated body fluids (SBF) for different periods up to 14 days at 37 °C. The results indicated that bioactivity of Ti–6Al–4V was dramatically improved after the deposition of β-Ta2O5, since the coating has a higher apatite forming ability than the Ti–6Al–4V substrate. Finally, the electrochemical behavior of the β-Ta2O5 coating after soaking in SBF at 37 °C for 0, 3, 7, and 14 days was studied through potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). EIS measurements also confirm that the presence of a hydroxyapatite layer on the coating becomes thicker and denser during soaking in SBF. Moreover, the coating exhibits better corrosion resistance than the bare alloy. Hence, the β-Ta2O5 coating is a promising candidate coating for protection of orthopedic implants with enhanced bioactivity and corrosion resistance. |
Keywords: | Tantalum oxides; bioactivity; cytocompatibility; corrosion resistance; mechanical properties |
Description: | Available online 08 December 2017 |
Rights: | © 2017 Elsevier Ltd and Techna Group S.r.l. All rights reserved. |
DOI: | 10.1016/j.ceramint.2017.12.040 |
Grant ID: | http://purl.org/au-research/grants/arc/DP150102417 |
Published version: | http://dx.doi.org/10.1016/j.ceramint.2017.12.040 |
Appears in Collections: | Aurora harvest 3 Mechanical Engineering publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.