Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/11364
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Type: Journal article
Title: The citropin peptides from the skin glands of the Australian Blue Mountains tree frog Litoria citropa. Part 2: sequence determination using electrospray mass spectrometry
Author: Wabnitz, P.
Bowie, J.
Wallace, J.
Tyler, M.
Citation: Rapid Communications in Mass Spectrometry, 1999; 13(17):1724-1732
Publisher: John Wiley
Issue Date: 1999
ISSN: 0951-4198
1097-0231
Abstract: A combination of electrospray mass spectrometry, Lys-C digest/mass spectrometry and automated Edman sequencing provides the amino acid sequences of nineteen citropin peptides isolated from the granular dorsal and submental glands of the Blue Mountains tree frog Litoria citropa. Citropin 1.1 [Gly Leu Phe Asp Val Ile Lys Lys Val Ala Ser Val Ile Gly Gly Leu (NH(2))] and citropin 1.2 [Gly Leu Phe Asp Ile Ile Lys Lys Val Ala Ser Val Val Gly Gly Leu (NH(2))] are the two major skin peptides: both show significant wide-spectrum antibacterial activity.
Keywords: Skin; Animals; Anura; Peptides; Antimicrobial Cationic Peptides; Amphibian Proteins; Sequence Analysis; Amino Acid Sequence; Molecular Sequence Data; Australia; Mass Spectrometry
Rights: Copyright © 1999 John Wiley & Sons, Ltd.
RMID: 0030004366
DOI: 10.1002/(SICI)1097-0231(19990915)13:17<1724::AID-RCM706>3.0.CO;2-T
Appears in Collections:Biochemistry publications

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