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https://hdl.handle.net/2440/10582
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Type: | Journal article |
Title: | Craniopharyngioma: a review of long-term visual outcome |
Author: | Chen, C. Okera, S. Davies, P. Selva-Nayagam, D. Crompton, J. |
Citation: | Clinical and Experimental Ophthalmology, 2003; 31(3):220-228 |
Publisher: | Blackwell Publishing Asia |
Issue Date: | 2003 |
ISSN: | 1442-6404 1442-9071 |
Abstract: | <h4>Purpose</h4>To assess the clinical presentation and long-term visual outcome in a series of patients with craniopharyn-gioma.<h4>Methods</h4>Retrospective case review.<h4>Results</h4>Thirty-six patients were reviewed, comprising 19 female patients and 17 male patients. The age range was 2-77 years with a bimodal distribution of 17 children (mean age 10 years) and 19 adults (mean age 47 years). Blurred vision was the most common visual complaint (23 cases, 64%) and headache the most frequent systemic complaint (19 cases, 53%). The average duration of systemic symptoms was 45 weeks compared to 10 weeks for visual symptoms. Deficits in visual acuity occurred in 13 patients (36%) and showed no significant change from initial presentation to final review. Sixteen patients (44%) had bitemporal hemianopia on presentation and pleomorphism (change from one type of visual field defect to another) occurred in 11 patients. Recurrence of tumour occurred in 15 patients (42%) and was more likely in children (59%) than adults (26%). The mean time period to recurrence was 7 years. The average follow-up period for all cases was 10 years.<h4>Conclusion</h4>Patients with craniopharyngioma generally present late, and the visual symptoms are often preceded by a long history of systemic symptoms. Children are more likely to present with systemic symptoms than adults. Visual field pleomorphism is a feature of craniopharyngioma and occurred in one-third of the patients. Local recurrence is common. Although magnetic resonance imaging is the recommended means of follow up, regular neuro-ophthalmic review is useful in the early detection of anterior visual pathway compression by recurrent tumour. |
Keywords: | Fundus Oculi Humans Craniopharyngioma Pituitary Neoplasms Neoplasm Recurrence, Local Vision Disorders Hemianopsia Postoperative Complications Tomography, X-Ray Computed Magnetic Resonance Imaging Treatment Outcome Retrospective Studies Follow-Up Studies Visual Acuity Visual Fields Adolescent Adult Aged Middle Aged Child Child, Preschool Female Male Vision, Ocular |
DOI: | 10.1046/j.1442-9071.2003.00648.x |
Published version: | http://dx.doi.org/10.1046/j.1442-9071.2003.00648.x |
Appears in Collections: | Aurora harvest 7 Surgery publications |
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