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https://hdl.handle.net/2440/10273
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Type: | Journal article |
Title: | Laparoscopic-assisted resection of colorectal malignancies: A systematic review |
Author: | Chapman, A. Levitt, M. Hewett, P. Woods, R. Sheiner, H. Maddern, G. |
Citation: | Annals of Surgery, 2001; 234(5):590-606 |
Publisher: | Lippincott Williams & Wilkins |
Issue Date: | 2001 |
ISSN: | 0003-4932 1528-1140 |
Statement of Responsibility: | Andrew E. Chapman, Michael D. Levitt, Peter Hewett, Rodney Woods, Harry Sheiner and Guy J. Maddern, |
Abstract: | Objective: To compare the safety and efficacy of laparoscopic-assisted resection of colorectal malignancies with open colectomy. Methods: Two search strategies were devised to retrieve literature from the Medline, Current Contents, Embase, and Cochrane Library databases until July 1999. Inclusion of papers was determined using a predetermined protocol, independent assessments by two reviewers, and a final consensus decision. English language papers were selected. Acceptable study designs included randomized controlled trials, controlled clinical trials, case series, or case reports. Fifty-two papers met the inclusion criteria. They were tabulated and critically appraised in terms of methodology and design, outcomes, and the possible influence of bias, confounding, and chance. Results: Little high-level evidence was available. Laparoscopic resection of colorectal malignancy was more expensive and time-consuming, but little evidence suggests high rates of port site recurrence. The new procedure’s advantages revolve around early recovery from surgery and reduced pain. Conclusions: The evidence base for laparoscopic-assisted resection of colorectal malignancies is inadequate to determine the procedure’s safety and efficacy. Because of inadequate evidence detailing circumferential marginal clearance of tumors and the necessity of determining a precise incidence of cardiac and other major complications, along with wound and port site recurrence, it is recommended that a controlled clinical trial, ideally with random allocation to an intervention and control group, be conducted. Long-term survival rates need to be a primary aim of such a trial. |
Keywords: | Humans Colorectal Neoplasms Laparoscopy Colectomy Lymph Node Excision Survival Rate Risk Factors |
Description: | Copyright © 2001 Lippincott Williams & Wilkins, Inc. |
DOI: | 10.1097/00000658-200111000-00003 |
Published version: | http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1422083 |
Appears in Collections: | Aurora harvest 7 Surgery publications |
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