Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/100249
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Relating intercellular variability in nanoparticle uptake with biological consequence: a quantitative x-ray fluorescence study for radiosensitization of cells |
Author: | Turnbull, T. Douglass, M. Paterson, D. Bezak, E. Thierry, B. Kempson, I. |
Citation: | Analytical Chemistry, 2015; 87(21):10693-10697 |
Publisher: | American Chemical Society |
Issue Date: | 2015 |
ISSN: | 0003-2700 1520-6882 |
Statement of Responsibility: | Tyron Turnbull, Michael Douglass, David Paterson, Eva Bezak, Benjamin Thierry, and Ivan Kempson |
Abstract: | Internalized gold nanoparticles were quantified in large numbers of individual prostate cancer cells using large area synchrotron X-ray fluorescence microscopy. Cells were also irradiated with a 6 MV linear accelerator to assess the biological consequence of radiosensitization with gold nanoparticles. A large degree of heterogeneity in nanoparticle uptake between cells resulted in influenced biological effect. |
Keywords: | Cells Humans Prostatic Neoplasms Gold Light Fluorescence X-Rays Male Metal Nanoparticles |
Rights: | © 2015 American Chemical Society |
DOI: | 10.1021/acs.analchem.5b03183 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1045841 |
Published version: | http://dx.doi.org/10.1021/acs.analchem.5b03183 |
Appears in Collections: | Aurora harvest 7 Physics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.