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PreviewIssue DateTitleAuthor(s)
2013Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-c and extracellular cyclic guanosine 3′,5′-monophosphateCastro, J.; Harrington, A.; Hughes, P.; Martin, C.; Ge, P.; Shea, C.; Jin, H.; Jacobson, S.; Hannig, G.; Mann, E.; Cohen, M.; MacDougall, J.; Lavins, B.; Kurtz, C.; Silos-Santiago, I.; Johnston, J.; Blackshaw, L.; Brierley, S.
2011Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver diseaseEbrahimkhani, M.; Oakley, F.; Murphy, L.; Mann, J.; Moles, A.; Perugorria, M.; Ellis, E.; Lakey, A.; Burt, A.; Douglass, A.; Wright, M.; White, S.; Jaffre, F.; Maroteaux, L.; Mann, D.
2019CBE1 is a manchette- and mitochondria-associated protein with a potential role in somatic cell proliferationPleuger, C.; Lehti, M.S.; Cooper, M.; O'Connor, A.E.; Merriner, D.J.; Smyth, I.M.; Cottle, D.L.; Fietz, D.; Bergmann, M.; O'Bryan, M.K.
2017Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signallingHughes, J.; Dawson, R.; Tea, M.; McAninch, D.; Piltz, S.; Jackson, D.; Stewart, L.; Ricos, M.; Dibbens, L.; Harvey, N.; Thomas, P.
2017NAD deficiency, congenital malformations, and niacin supplementationShi, H.; Enriquez, A.; Rapadas, M.; Martin, E.; Wang, R.; Moreau, J.; Lim, C.; Szot, J.; Ip, E.; Hughes, J.; Sugimoto, K.; Humphreys, D.; McInerney-Leo, A.; Leo, P.; Maghzal, G.; Halliday, J.; Smith, J.; Colley, A.; Mark, P.; Collins, F.; et al.
2017Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancerPonnusamy, S.; Coss, C.; Thiyagarajan, T.; Watts, K.; Hwang, D.-J.; He, Y.; Selth, L.; McEwan, I.; Duke, C.; Pagadala, J.; Singh, G.; Wake, R.; Ledbetter, C.; Tilley, W.; Moldoveanu, T.; Dalton, J.; Miller, D.; Narayanan, R.
2020Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editingMcCarron, A.; Cmielewski, P.; Reyne, N.; McIntyre, C.; Finnie, J.; Craig, F.; Rout-Pitt, N.; Delhove, J.; Schjenken, J.E.; Chan, H.Y.; Boog, B.; Knight, E.; Gilmore, R.C.; O'Neal, W.K.; Boucher, R.C.; Parsons, D.; Donnelley, M.
2020Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletionKohno, S.; Linn, P.; Nagatani, N.; Watanabe, Y.; Kumar, S.; Soga, T.; Takahashi, C.
2017DR5 and caspase-8 are dispensable in ER stress-induced apoptosisGlab, J.; Doerflinger, M.; Nedeva, C.; Jose, I.; Mbogo, G.; Paton, J.; Paton, A.; Kueh, A.; Herold, M.; Huang, D.; Segal, D.; Brumatti, G.; Puthalakath, H.
2012A Combination of Local Inflammation and Central Memory T Cells Potentiates Immunotherapy in the SkinFiorenza, S.; Kenna, T.; Comerford, I.; McColl, S.; Steptoe, R.; Leggatt, G.; Frazer, I.