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Type: Conference paper
Title: Fibre-optic photochemical stroke: generating and measuring photochemical changes inside the brain
Author: Tsiminis, G.
Klarić, T.
Schartner, E.
Warren-Smith, S.
Lewis, M.
Koblar, S.
Monro, T.
Citation: Proceedings of SPIE, 2014 / LopezHiguera, J., Jones, J., LopezAmo, M., Santos, J. (ed./s), vol.9157, pp.9157D4-1-9157D4-4
Publisher: SPIE
Issue Date: 2014
Series/Report no.: Proceedings of SPIE
ISBN: 9781628411751
ISSN: 0277-786X
Conference Name: 23rd International Conference on Optical Fibre Sensors (2 Jun 2014 - 6 Jun 2014 : Santander, Spain)
Editor: LopezHiguera, J.
Jones, J.
LopezAmo, M.
Santos, J.
Statement of
G. Tsiminis, T. S. Klarić, E. P. Schartner, S. C. Warren-Smith, M. D. Lewis, S. A. Koblar, T. M. Monro
Abstract: We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal
Keywords: Optical fibre sensor; photochemical stroke; in-vivo sensor; fluorescence detection
Rights: © 2014 SPIE
DOI: 10.1117/12.2071261
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