Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9229
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBoyd, K.en
dc.contributor.authorO'Donovan, D.en
dc.contributor.authorDoran, S.en
dc.contributor.authorWishart, J.en
dc.contributor.authorChapman, I.en
dc.contributor.authorHorowitz, M.en
dc.contributor.authorFeinle-Bisset, C.en
dc.date.issued2003en
dc.identifier.citationAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2003; 284(2):G188-G196en
dc.identifier.issn0193-1857en
dc.identifier.issn1522-1547en
dc.identifier.urihttp://hdl.handle.net/2440/9229-
dc.descriptionPublished abstract used with permission of the copyright owner.en
dc.description.abstractThere is evidence that gastrointestinal function adapts in response to a highfat (HF) diet. This study investigated the hypothesis that an HF diet modifies the acute effects of duodenal lipid on appetite, antropyloroduodenal pressures, plasma CCK and plasma glucagon-like peptide-1 (GLP-1) levels in humans. Twelve healthy men were studied twice in randomized, crossover fashion. The effects of a 90-min duodenal lipid infusion (6.3 kJ/min) on the above parameters were assessed immediately following 14-day periods on either an HF or a low-fat (LF) diet. After the HF diet, pyloric tonic and phasic pressures were attenuated, and the number of antropyloroduodenal pressure-wave sequences was increased when compared with the LF diet. Plasma CCK and GLP-1 levels did not differ between the two diets. Hunger was greater during the lipid infusion following the HF diet, but there was no difference in food intake. Therefore, exposure to an HF diet for 14 days attenuates the effects of duodenal lipid on antropyloroduodenal pressures and hunger without affecting food intake or plasma hormone levels.en
dc.description.statementofresponsibilityK. A. Boyd, D. G. O'Donovan, S. Doran, J. Wishart, I. M. Chapman, M. Horowitz, and C. Feinleen
dc.language.isoenen
dc.publisherAmer Physiological Socen
dc.rights© 2003 American Physiological Societyen
dc.subjectantropyloroduodenal pressures; cholecystokinin; glucose-like peptide-1; energy intakeen
dc.titleHigh-fat diet effects on gut motility, hormone, and appetite responses to duodenal lipid in healthy menen
dc.typeJournal articleen
dc.identifier.rmid0020030364en
dc.identifier.doi10.1152/ajpgi.00375.2002en
dc.identifier.pubid58873-
pubs.library.collectionMedicine publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]en
dc.identifier.orcidFeinle-Bisset, C. [0000-0001-6848-0125]en
Appears in Collections:Medicine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.