Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/87412
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dc.contributor.authorKalionis, B.-
dc.contributor.authorDodd, I.B.-
dc.contributor.authorEgan, J.B.-
dc.date.issued1986-
dc.identifier.citationJournal of Molecular Biology, 1986; 191(2):199-209-
dc.identifier.issn0022-2836-
dc.identifier.issn1089-8638-
dc.identifier.urihttp://hdl.handle.net/2440/87412-
dc.description.abstractThe PstI fragment (65.5% to 77.4%) of coliphage 186, known genetically to encode the major control genes, has been sequenced, and an analysis performed to assess coding capacity, transcription-translation signals, and to identify any other significant features. Our analysis indicates that the region encodes: (1) seven genes, including the int and cI genes, which overlap, the late control gene B, and two genes, named CP75 and CP76, encoding potential DNA-binding proteins; (2) a promoter pB and terminator tB for the rightward transcription of the B gene, and we predict the existence of this transcript in a lysogen; (3) a promoter pL and terminator tL for leftward transcription that encodes the int and cI genes, and represents the presumed lysogenic transcript; (4) a promoter pR for rightward transcription to give the presumed (early) lytic transcript that is overlapping and convergent with the lysogenic transcript; and finally (5), a potential operator site for repressor binding in the region of the pR promoter. Preliminary evidence is presented to support this analysis.-
dc.description.statementofresponsibilityBill Kalionis, Ian B. Dodd, J.Barry Egan-
dc.language.isoen-
dc.publisherElsevier-
dc.rights© 1986 Academic Press, Inc.-
dc.source.urihttp://dx.doi.org/10.1016/0022-2836(86)90257-3-
dc.subjectRibosomes-
dc.subjectColiphages-
dc.subjectDNA, Viral-
dc.subjectTranscription, Genetic-
dc.subjectGene Expression Regulation-
dc.subjectBinding Sites-
dc.subjectBase Sequence-
dc.subjectRepetitive Sequences, Nucleic Acid-
dc.subjectPromoter Regions, Genetic-
dc.subjectTerminator Regions, Genetic-
dc.titleControl of gene expression in the P2-related template coliphages-
dc.typeJournal article-
dc.identifier.doi10.1016/0022-2836(86)90257-3-
pubs.publication-statusPublished-
dc.identifier.orcidDodd, I.B. [0000-0003-2969-6841]-
Appears in Collections:Aurora harvest 7
Biochemistry publications

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