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Type: Journal article
Title: Localization of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum in merozoites and ring-infected erythrocytes
Author: Brown, G.V.
Culvenor, J.G.
Crewther, P.E.
Bianco, A.E.
Coppel, R.L.
Saint, R.B.
Stahl, H.D.
Kemp, D.J.
Anders, R.F.
Citation: Journal of Experimental Medicine, 1985; 162(2):774-779
Publisher: Rockefeller University Press
Issue Date: 1985
ISSN: 0022-1007
Statement of
G V Brown, J G Culvenor, P E Crewther, A E Bianco, R L Coppel, R B Saint, H D Stahl, D J Kemp, and R F Anders
Abstract: Immunoelectron microscopy with protein A gold has been used to determine the subcellular location of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum. RESA was associated with dense vesicles presumed to be micronemes within merozoites. RESA was not detected on the surface of merozoites but was located at the membrane of erythrocytes infected with ring-stage parasites. RESA within merozoites was largely soluble in the nonionic detergent Triton X-100, but was insoluble in this detergent when associated with the erythrocyte membrane.
Keywords: Erythrocytes
Plasmodium falciparum
Antigens, Protozoan
Antigens, Surface
Microscopy, Electron
Rights: © 1985 Rockefeller University Press
DOI: 10.1084/jem.162.2.774
Appears in Collections:Aurora harvest 2
Molecular and Biomedical Science publications

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