Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/82884
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | A dip biosensor based on localized surface plasmon resonance at the tip of an optical fiber |
Author: | Sciacca, B. Monro, T. |
Citation: | Langmuir: the ACS journal of surfaces and colloids, 2014; 30(3):946-954 |
Publisher: | American Chemical Society |
Issue Date: | 2014 |
ISSN: | 0743-7463 1520-5827 |
Organisation: | Institute for Photonics & Advanced Sensing (IPAS) |
Statement of Responsibility: | Beniamino Sciacca and Tanya M. Monro |
Abstract: | A dip biosensor is realized by depositing metallic nanoparticles onto the tip of a cleaved optical fiber. Light coupled into the fiber interacts with the localized surface plasmons within the nanoparticles at the tip; a portion of the scattered light recouples into the optical fiber and is analyzed by a spectrometer. Characterization of the sensor demonstrates an inverse relationship between the sensitivity and the number of particles deposited onto the surface, with smaller quantities leading to greater sensitivity. The results obtained showed also that by depositing nanoparticles with distinct localized surface plasmon resonance signatures with limited overlap, as for the case of gold and silver nanospheres, a multiplexed dip biosensor can be realized by simply functionalizing the different nanoparticles with different antibodies after the fashion of an immunoassay. In this way different localized surface plasmons resonance bands responsive to different target analytes can be separately monitored, as further presented below, requiring a minimal quantity of reagents both for the functionalization process and for the sample analysis. |
Keywords: | Gold Silver Surface Plasmon Resonance Biosensing Techniques Particle Size Surface Properties Metal Nanoparticles Optical Fibers |
Rights: | © 2014 American Chemical Society |
DOI: | 10.1021/la403667q |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1010728 |
Published version: | http://dx.doi.org/10.1021/la403667q |
Appears in Collections: | Aurora harvest 7 IPAS publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.