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Type: Journal article
Title: Assessment of atrial septal defects in adults comparing cardiovascular magnetic resonance with transoesophageal echocardiography
Author: Teo, K.
Disney, P.
Dundon, B.
Worthley, M.
Brown, M.
Sanders, P.
Worthley, S.
Citation: Journal of Cardiovascular Magnetic Resonance, 2010; 12(1):44-1-44-6
Publisher: Marcel Dekker Inc
Issue Date: 2010
ISSN: 1097-6647
Statement of
Karen S.L. Teo, Patrick J. Disney, Benjamin K. Dundon, Matthew I. Worthley, Michael A. Brown, Prashanthan Sanders and Stephen G. Worthley
Abstract: BACKGROUND: Many adult patients with secundum-type atrial septal defects (ASDs) are able to have these defects fixed percutaneously. Traditionally, this has involved an assessment of ASD size, geometry and atrial septal margins by transoesophageal echocardiography (TOE) prior to percutaneous closure. This is a semi-invasive technique, and all of the information obtained could potentially be obtained by non-invasive cardiovascular magnetic resonance (CMR). We compared the assessment of ASDs in consecutive patients being considered for percutaneous ASD closure using CMR and TOE. METHODS: Consecutive patients with ASDs diagnosed on transthoracic echocardiography (TTE) were invited to undergo both CMR and TOE. Assessment of atrial septal margins, maximal and minimal defect dimensions was performed with both techniques. Analyses between CMR and TOE were made using simple linear regression and Bland Altman Analyses. RESULTS: Total CMR scan time was 20 minutes, and comparable to the TOE examination time. A total of 20 patients (M:F = 5:15, mean age 42.8 years +/- 15.7) were included in the analyses. There was an excellent agreement between CMR and TOE for estimation of maximum defect size (R = 0.87). The anterior inferior, anterior superior and posterior inferior margins could be assessed in all patients with CMR. The posterior superior margin could not be assessed in only one patient. Furthermore, in 1 patient in whom TOE was unable to be performed, CMR was used to successfully direct percutaneous ASD closure. CONCLUSIONS: CMR agrees with TOE assessment of ASDs in the work-up for percutaneous closure. Potentially CMR could be used instead of TOE for this purpose.
Keywords: Humans; Heart Septal Defects, Atrial; Magnetic Resonance Imaging; Echocardiography, Transesophageal; Adult; Middle Aged; Female; Male
Rights: © 2010 Teo et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
RMID: 0020100950
DOI: 10.1186/1532-429X-12-44
Appears in Collections:Medicine publications

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