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Type: Journal article
Title: Second-generation highly cross-linked X3™ polyethylene wear: A preliminary radiostereometric analysis study
Other Titles: Second-generation highly cross-linked X3(TM) polyethylene wear: A preliminary radiostereometric analysis study
Author: Campbell, D.
Field, J.
Callary, S.
Citation: Clinical Orthopaedics and Related Research, 2010; 468(10):2704-2709
Publisher: Lippincott Williams & Wilkins
Issue Date: 2010
ISSN: 0009-921X
Statement of
David G. Campbell, John R. Field and Stuart A. Callary
Abstract: Background: First-generation highly cross-linked polyethylene liners have reduced the incidence of wear particle-induced osteolysis. However, failed acetabular liners have shown evidence of surface cracking, mechanical failure, and oxidative damage. This has led to the development of second-generation highly cross-linked polyethylene, which has improved wear and mechanical properties and resistance to oxidation in vitro. Owing to its recent introduction, there are no publications describing its clinical performance. Questions/purposes: We assessed early clinical wear of a second-generation highly cross-linked polyethylene liner and compared its clinical performance with the published results of hip simulator tests and with first-generation highly cross-linked polyethylene annealed liners. Patients and Methods: Twenty-one patients were enrolled in a prospective cohort study. Clinical outcome and femoral head penetration were measured for 19 patients at 6 months and 1 and 2 years postoperatively. Results: The median proximal head penetration was 0.009 mm and 0.024 mm at 1 and 2 years, respectively. The median two-dimensional (2-D) head penetration was 0.083 mm and 0.060 mm at 1 and 2 years, respectively. The median proximal wear rate between 1 and 2 years was 0.015 mm/year. Conclusions: The wear rate calculated was similar to the in vitro wear rate reported for this material; however, it was less than the detection threshold for this technique. Although longer followup is required for wear to reach a clinically quantifiable level, this low level of wear is encouraging for the future clinical performance of this material.
Keywords: Hip Joint
Osteoarthritis, Hip
Prosthesis Failure
Range of Motion, Articular
Treatment Outcome
Arthroplasty, Replacement, Hip
Prospective Studies
Prosthesis Design
Hip Prosthesis
Recovery of Function
Surface Properties
Stress, Mechanical
Gamma Rays
Time Factors
Middle Aged
South Australia
Rights: © The Association of Bone and Joint Surgeons ® 2010
DOI: 10.1007/s11999-010-1259-y
Appears in Collections:Aurora harvest 5
Orthopaedics and Trauma publications

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