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|Title:||Second-generation highly cross-linked X3™ polyethylene wear: A preliminary radiostereometric analysis study|
|Other Titles:||Second-generation highly cross-linked X3(TM) polyethylene wear: A preliminary radiostereometric analysis study|
|Citation:||Clinical Orthopaedics and Related Research, 2010; 468(10):2704-2709|
|Publisher:||Lippincott Williams & Wilkins|
|David G. Campbell, John R. Field and Stuart A. Callary|
|Abstract:||Background: First-generation highly cross-linked polyethylene liners have reduced the incidence of wear particle-induced osteolysis. However, failed acetabular liners have shown evidence of surface cracking, mechanical failure, and oxidative damage. This has led to the development of second-generation highly cross-linked polyethylene, which has improved wear and mechanical properties and resistance to oxidation in vitro. Owing to its recent introduction, there are no publications describing its clinical performance. Questions/purposes: We assessed early clinical wear of a second-generation highly cross-linked polyethylene liner and compared its clinical performance with the published results of hip simulator tests and with first-generation highly cross-linked polyethylene annealed liners. Patients and Methods: Twenty-one patients were enrolled in a prospective cohort study. Clinical outcome and femoral head penetration were measured for 19 patients at 6 months and 1 and 2 years postoperatively. Results: The median proximal head penetration was 0.009 mm and 0.024 mm at 1 and 2 years, respectively. The median two-dimensional (2-D) head penetration was 0.083 mm and 0.060 mm at 1 and 2 years, respectively. The median proximal wear rate between 1 and 2 years was 0.015 mm/year. Conclusions: The wear rate calculated was similar to the in vitro wear rate reported for this material; however, it was less than the detection threshold for this technique. Although longer followup is required for wear to reach a clinically quantifiable level, this low level of wear is encouraging for the future clinical performance of this material.|
|Keywords:||Hip Joint; Humans; Osteoarthritis, Hip; Prosthesis Failure; Polyethylene; Range of Motion, Articular; Treatment Outcome; Arthroplasty, Replacement, Hip; Prospective Studies; Prosthesis Design; Hip Prosthesis; Recovery of Function; Surface Properties; Stress, Mechanical; Gamma Rays; Time Factors; Aged; Middle Aged; South Australia; Female; Male|
|Rights:||© The Association of Bone and Joint Surgeons ® 2010|
|Appears in Collections:||Orthopaedics and Trauma publications|
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