Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/60714
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Type: Journal article
Title: Are adolescents dying by suicide taking SSRI antidepressants? A review of observational studies
Author: Dudley, M.
Goldney, R.
Hadzi-Pavlovic, D.
Citation: Australasian Psychiatry, 2010; 18(3):242-245
Publisher: Informa Healthcare-Taylor & Francis
Issue Date: 2010
ISSN: 1039-8562
1440-1665
Statement of
Responsibility: 
Michael Dudley, Robert Goldney and Dusan Hadzi-Pavlovic
Abstract: OBJECTIVE: The aim of this study was to examine the association between adolescents who die by suicide and their use of SSRI antidepressants. METHOD: We sought all available observational studies of individual adolescent suicides that were population based and which contained individual data on SSRIs at or around the time of death. RESULTS: From an initial database of 656 studies, we identified and examined six studies. In the latter, nine of 574 young people (1.6%) who died by suicide had had recent exposure to SSRIs. CONCLUSION: The rarity of SSRI usage prior to adolescent suicide is not supportive of the assertion that SSRIs are associated with increased suicide in young people. Given the prevalence of depression associated with youth suicide, it favours the conclusion that most adolescents dying by suicide have not had the potential benefit of antidepressants at the time of their deaths. This finding should allow practitioners, with appropriate precautions and as part of a comprehensive management plan, to more confidently prescribe SSRIs for young people with moderate to severe clinical depression.
Keywords: Adolescent; antidepressant; selective serotonin reuptake inhibitors; suicide; young people
Rights: © 2010 The Royal Australian and New Zealand College of Psychiatrists
RMID: 0020097966
DOI: 10.3109/10398561003681319
Appears in Collections:Psychiatry publications

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