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PreviewIssue DateTitleAuthor(s)
2017Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signallingHughes, J.; Dawson, R.; Tea, M.; McAninch, D.; Piltz, S.; Jackson, D.; Stewart, L.; Ricos, M.; Dibbens, L.; Harvey, N.; Thomas, P.
2017Epiregulin and EGFR interactions are involved in pain processingMartin, L.J.; Smith, S.B.; Khoutorsky, A.; Magnussen, C.A.; Samoshkin, A.; Sorge, R.E.; Cho, C.; Yosefpour, N.; Sivaselvachandran, S.; Tohyama, S.; Cole, T.; Khuong, T.M.; Mir, E.; Gibson, D.G.; Wieskopf, J.S.; Sotocinal, S.G.; Austin, J.S.; Meloto, C.B.; Gitt, J.H.; Gkogkas, C.; et al.
2017Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitorsPremarathne, S.; Murtaza, M.; Matigian, N.; Jolly, L.; Wood, S.
2017Peroxidase enzymes inhibit osteoclast differentiation and bone resorptionPanagopoulos, V.; Liapis, V.; Zinonos, I.; Hay, S.; Leach, D.A.; Ingman, W.; DeNichilo, M.O.; Atkins, G.J.; Findlay, D.M.; Zannettino, A.C.W.; Evdokiou, A.
2017Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.Powell, J.; Lewis, A.; Zhu, W.; Toubia, J.; Pitman, M.; Wallington-Beddoe, C.; Moretti, P.; Iarossi, D.; Samaraweera, S.; Cummings, N.; Ramshaw, H.; Thomas, D.; Wei, A.; Lopez, A.; D'Andrea, R.; Lewis, I.; Pitson, S.
2017USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitorsBridges, C.; Tan, M.; Premarathne, S.; Nanayakkara, D.; Bellette, B.; Zencak, D.; Domingo, D.; Gecz, J.; Murtaza, M.; Jolly, L.; Wood, S.
2017A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactationOakes, S.R.; Gallego-Ortega, D.; Stanford, P.M.; Junankar, S.; Au, W.W.Y.; Kikhtyak, Z.; von Korff, A.; Sergio, C.M.; Law, A.M.K.; Castillo, L.E.; Allerdice, S.L.; Young, A.I.J.; Piggin, C.; Whittle, B.; Bertram, E.; Naylor, M.J.; Roden, D.L.; Donovan, J.; Korennykh, A.; Goodnow, C.C.; et al.; Wells, C.A.
2017Disrupting androgen receptor signaling induces Snail-mediated epithelial-mesenchymal plasticity in prostate cancerMiao, L.; Yang, L.; Li, R.; Rodrigues, D.; Crespo, M.; Hsieh, J.; Tilley, W.; De Bono, J.; Selth, L.; Raj, G.