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Issue Date
Title
Author(s)
2010
Selective escalation of imatinib therapy and early switching to nilotinib in de novo chronic phase CML patients: interim results from the TIDELL-II trial
Yeung, D.
;
Osborn, M.
;
White, D.
;
Branford, S.
;
Haswell, L.
;
Slader, C.
;
Issa, S.
;
Hiwase, D.
;
Hertzberg, M.
;
Schwarer, A.
;
Filshie, R.
;
Arthur, C.
;
Kwan, Y.
;
Forsyth, C.
;
Ross, D.
;
Mills, A.
;
Grigg, A.
;
Hughes, T.
;
Annual Meeting of the American Society of Hematology (52nd : 2010 : Orlando, Fl.)
2010
Nilotinib does not significantly reduce imatinib OCT-1 activity in either cell lines or primary CML cells
Eadie, L.
;
Hughes, T.
;
White, D.
2010
Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: implications for combination TKI therapy
Hiwase, D.
;
White, D.
;
Zrim, S.
;
Saunders, V.
;
Vaz de Melo, J.
;
Hughes, T.
2010
Chronic Myeloid Leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 Activity
Engler, J.
;
Frede, A.
;
Saunders, V.
;
Zannettino, A.
;
Hughes, T.
;
White, D.
2010
Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors
Hiwase, D.
;
White, D.
;
Powell, J.
;
Saunders, V.
;
Zrim, S.
;
Frede, A.
;
Guthridge, M.
;
Lopez, A.
;
D'Andrea, R.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
2010
The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34⁺ cells
Engler, J.
;
Frede, A.
;
Saunders, V.
;
Zannettino, A.
;
White, D.
;
Hughes, T.
2010
Plasma adiponectin levels are markedly elevated in imatinib-treated chronic myeloid leukemia (CML) patients: A mechanism for improved insulin sensitivity in Type 2 diabetic CML patients?
Fitter, S.
;
Vandyke, K.
;
Schultz, C.
;
White, D.
;
Hughes, T.
;
Zannettino, A.
2010
Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with Imatinib
White, D.
;
Dang, P.
;
Engler, J.
;
Frede, A.
;
Osborn, M.
;
Saunders, V.
;
Manley, P.
;
Zrim, S.
;
Hughes, T.
Discover
Author
5
Saunders, V.
4
Frede, A.
3
Engler, J.
3
Hiwase, D.
3
Zannettino, A.
3
Zrim, S.
2
Osborn, M.
2
Vaz de Melo, J.
1
Annual Meeting of the American So...
1
Arthur, C.
.
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Subject
5
Humans
5
Pyrimidines
4
Benzamides
4
Imatinib Mesylate
4
Leukemia, Myelogenous, Chronic, B...
4
Piperazines
3
Protein Kinase Inhibitors
3
Treatment Outcome
2
Analysis of Variance
2
Antineoplastic Agents
.
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