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https://hdl.handle.net/2440/58964
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Type: | Journal article |
Title: | The current role of PET-CT in the characterization of hepatobiliary malignancies |
Author: | Garcea, G. Ong, S. Maddern, G. |
Citation: | Hepato Pancreato Biliary, 2009; 11(1):4-17 |
Publisher: | Isis Medical Media Ltd. |
Issue Date: | 2009 |
ISSN: | 1365-182X 1477-2574 |
Statement of Responsibility: | Ginseppe Garcea, Seok Ling Ong and Guy J. Maddern |
Abstract: | Background: Surgery has become heavily dependent on accurate imaging in the assessment and treatment of suspected or confirmed intra-abdominal malignancy. Positron emission tomographycomputed tomography (PET-CT) fuses uptake of a radiotracer combined with CT images to assess both functional tissue activity and anatomical detail. Since its introduction it has offered new ways of treating gastrointestinal cancers. Methods: The review analyses the present literature regarding the use of PET-CT in the assessment, diagnosis, staging and treatment of hepatobiliary malignancies. Results: PET-CT is widely used in pre-operative tumours staging for colorectal liver metastases. There is convincing data that it may also be applicable for neuroendocrine tumours, assessment of indeterminate pancreas lesions and clinical drug trials. PET-CT is of limited value in hepatocellular cancers, although new techniques in dual-tracer PET-CT may change this. Conclusion: Knowledge of the strengths and limitations of PET-CT is important for all surgeons managing cancer of the hepatobiliary system. More clinical data are required on PET-CT, particularly its effect on long-term survival in PET-CT-staged patients undergoing resection. |
Keywords: | PET/CT CT/PET colorectal cancer colorectal hepatic metastases hepatocellular cancer pancreatic cancer cholangiocarcinoma gallbladder cancer neuroendocrine cyst |
Rights: | © 2009 International Hepato-Pancreato-Biliary Association |
DOI: | 10.1111/j.1477-2574.2008.00009.x |
Published version: | http://dx.doi.org/10.1111/j.1477-2574.2008.00009.x |
Appears in Collections: | Aurora harvest 5 Surgery publications |
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