Adelaide Research & Scholarship
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https://hdl.handle.net/2440/34890
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| Type: | Journal article |
| Title: | Ring-deactivated hydroxymethylpyrroles as inhibitors of α-chymotrypsin |
| Other Titles: | Ring-deactivated hydroxymethylpyrroles as inhibitors of alpha-chymotrypsin |
| Author: | Abell, A. Nabbs, B. |
| Citation: | Bioorganic and Medicinal Chemistry, 2001; 9(3):621-628 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Issue Date: | 2001 |
| ISSN: | 0968-0896 1464-3391 |
| Statement of Responsibility: | Andrew D. Abell, and Brent K. Nabbs |
| Abstract: | N-Acyl and N-sulfonylhydroxymetyhylpyrroles have been synthesised and shown to inhibit α-chymotrypsin. A hydrophobic group in the N-substituent has been shown to be required for activity. |
| Keywords: | Animals Cattle Pyrroles Chymotrypsin Serine Proteinase Inhibitors Structure-Activity Relationship Kinetics |
| Rights: | Copyright © 2001 Elsevier Science Ltd. All rights reserved. |
| DOI: | 10.1016/S0968-0896(00)00274-1 |
| Description (link): | http://www.sciencedirect.com/science/journal/09680896 |
| Published version: | http://dx.doi.org/10.1016/s0968-0896(00)00274-1 |
| Appears in Collections: | Aurora harvest Chemistry publications |
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