Adelaide Research & Scholarship
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https://hdl.handle.net/2440/31044
| Type: | Book chapter |
| Title: | The 25-Hydroxyvitamin D 24-Hydroxylase |
| Author: | Omdahl, John L. May, B. |
| Citation: | Vitamin D / D. Feldman, F. H. Glorieux, J. W. Pike(eds.), pp.69-85 |
| Publisher: | Academic Press |
| Issue Date: | 1997 |
| ISBN: | 0122526856 |
| School/Discipline: | School of Molecular and Biomedical Science : Biochemistry |
| Abstract: | This chapter reviews the role of 25-hydroxyvitamin D 24-hydroxylase in vitamin D metabolism. The 24-hydroxylase enzyme is a widely distributed component of the vitamin D pathway. It is regulated by a spectrum of hormones and functions to synthesise 24-hydroxylated metabolites, with preferential action in promoting bone mineralization and possibly other undisclosed cellular functions that may become evident through the use of gene knockout models. It also plays a central role in directing the metabolic turnover of several 25-hydroxylated vitamin D metabolites. |
| Appears in Collections: | Biochemistry publications |
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