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PreviewIssue DateTitleAuthor(s)
2014AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniaePlumptre, C.; Eijkelkamp, B.; Morey, J.; Behr, F.; Couñago, R.; Ogunniyi, A.; Kobe, B.; O'Mara, M.; Paton, J.; McDevitt, C.
2014Imperfect coordination chemistry facilitates metal ion release in the Psa permeaseCounago, R.; Ween, M.; Begg, S.; Bajaj, M.; Zuegg, J.; O'Mara, M.; Cooper, M.; McEwan, A.; Paton, J.; Kobe, B.; McDevitt, C.
2015Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcALuo, Z.; Morey, J.; McDevitt, C.; Kobe, B.
2015Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopyDeplazes, E.; Begg, S.; van Wonderen, J.; Campbell, R.; Kobe, B.; Paton, J.; MacMillan, F.; McDevitt, C.; O'Mara, M.
2015Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approachBajaj, M.; Mamidyala, S.; Zuegg, J.; Begg, S.; Ween, M.; Luo, Z.; Huang, J.; McEwan, A.; Kobe, B.; Paton, J.; McDevitt, C.; Cooper, M.
2018An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysisRyan, T.; Trewhella, J.; Murphy, J.; Keown, J.; Casey, L.; Pearce, F.; Goldstone, D.; Chen, K.; Luo, Z.; Kobe, B.; McDevitt, C.; Watkin, S.; Hawley, A.; Mudie, S.; Samardzic Boban, V.; Kirby, N.
2011A molecular mechanism for bacterial susceptibility to zincMcDevitt, C.; Ogunniyi, A.; Valkov, E.; Lawrence, M.; Kobe, B.; McEwan, A.; Paton, J.; Imlay, J.
2012Prokaryotic substrate-binding proteins as targets for antimicrobial therapiesCounago, R.; McDevitt, C.; Ween, M.; Kobe, B.
2015Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniaeBegg, S.; Eijkelkamp, B.; Luo, Z.; Couñago, R.; Morey, J.; Maher, M.; Ong, C.; McEwan, A.; Kobe, B.; O'Mara, M.; Paton, J.; McDevitt, C.