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PreviewIssue DateTitleAuthor(s)
2007Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated effluxIgel, S.; Drescher, S.; Murdter, T.; Hofmann, U.; Heinkele, G.; Tegude, H.; Glaeser, H.; Brenner, S.; Somogyi, A.; Omari, T.; Schafer, C.; Eichelbaum, M.; Fromm, M.
2004Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicityColler, J.; Krebsfaenger, N.; Klein, K.; Wolbold, R.; Nussler, A.; Neuhaus, P.; Zanger, U.; Eichelbaum, M.; Murdter, T.
2007Predictive value of known and novel alleles ofCYP2B6 for efavirenz plasma concentrations in HIV-infected individualsRotger, M.; Tegude, H.; Colombo, S.; Cavassini, M.; Furrer, H.; Decosterd, L.; Blievernicht, J.; Saussele, T.; Gunthard, H.; Schwab, M.; Eichelbaum, M.; Telenti, A.; Zanger, U.
2001Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion techniquevon Richter, O.; Greiner, B.; Fromm, M.; Fraser, R.; Omari, T.; Barclay, M.; Dent, J.; Somogyi, A.; Eichelbaum, M.
2002Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transportersGlaeser, H.; Drescher, S.; Van der Kuip, H.; Behrens, C.; Geick, A.; Burk, O.; Dent, J.; Somogyi, A.; von Richter, O.; Griese, E.; Eichelbaum, M.; Fromm, M.
2009Genetic influences on the pharmacokinetics of orally and intravenously administered Digoxin as exhibited by monozygotic twinsBirkenfeld, A.; Jordan, J.; Hofmann, U.; Busjahn, A.; Franke, G.; Kruger, N.; Igel, S.; Murdter, T.; Drescher, S.; Shi, S.; Engeli, S.; Schwab, M.; Eichelbaum, M.; Luft, F.; Fromm, M.
2010The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P-glycoprotein) and consequences for the disposition of digoxinBurk, O.; Brenner, S.; Hofmann, U.; Tegude, H.; Igel, S.; Schwab, M.; Eichelbaum, M.; Alscher, M.
2004Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humansGlaeser, H.; Drescher, S.; Hofmann, U.; Heinkele, G.; Somogyi, A.; Eichelbaum, M.; Fromm, M.
2007Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypesSchroth, W.; Antoniadou, L.; Fritz, P.; Schwab, M.; Muerdter, T.; Zanger, U.; Simon, W.; Eichelbaum, M.; Brauch, H.
2010CYP2D6 polymorphisms as predictors of outcome in breast cancer patients treated with tamoxifen: Expanded polymorphism coverage improves risk stratificationSchroth, W.; Hamann, U.; Fasching, P.; Dauser, S.; Winter, S.; Eichelbaum, M.; Schwab, M.; Brauch, H.