Adelaide Research & Scholarship
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https://hdl.handle.net/2440/28540
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| Type: | Conference paper |
| Title: | Gene network analysis and design |
| Author: | Berryman, M. Allison, A. Abbott, D. |
| Citation: | Biomedical applications of micro- and nanoengineering II : 13-15 December 2004, Sydney, Australia / Dan V. Nicolau (ed.), pp. 126-133 |
| Publisher: | SPIE |
| Publisher Place: | Bellingham, Washington |
| Issue Date: | 2005 |
| Series/Report no.: | Proceedings of SPIE--the International Society for Optical Engineering ; 5651. |
| ISBN: | 081945611X |
| ISSN: | 1605-7422 |
| Conference Name: | Biomedical Applications of Micro- and Nanoengineering (2nd : 2004 : Sydney, Australia) |
| Editor: | Nicolau, D. |
| Statement of Responsibility: | Matthew J. Berryman, Andrew Allison, and Derek Abbott |
| Abstract: | Gene networks are composed of many different interacting genes and gene products (RNAs and proteins). They can be thought of as switching regions in n-dimensional space or as mass-balanced signaling networks. Both approaches allow for describing gene networks with the limited quantitative or even qualitative data available. We show how these approaches can be used in modeling the apoptosis gene network that has a vital role in tumor development. The open question is whether engineering changes to this network could be used as a possible cancer treatment. |
| Description: | © 2005 COPYRIGHT SPIE--The International Society for Optical Engineering |
| DOI: | 10.1117/12.582096 |
| Published version: | http://dx.doi.org/10.1117/12.582096 |
| Appears in Collections: | Aurora harvest 2 Electrical and Electronic Engineering publications |
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