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https://hdl.handle.net/2440/130723
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Type: | Journal article |
Title: | FRAIL scale: Predictive validity and diagnostic test accuracy |
Author: | Thompson, M.Q. Theou, O. Tucker, G.R. Adams, R.J. Visvanathan, R. |
Citation: | Australasian Journal on Ageing, 2020; 39(4):e529-e536 |
Publisher: | Wiley |
Issue Date: | 2020 |
ISSN: | 1440-6381 1741-6612 |
Statement of Responsibility: | Mark Q. Thompson, Olga Theou, Graeme R. Tucker, Robert J. Adams, Renuka Visvanathan |
Abstract: | OBJECTIVE: To examine the predictive validity of the FRAIL scale for mortality, and diagnostic test accuracy (DTA) against the frailty phenotype (FP). MEASUREMENT: Frailty was measured in 846 community-dwelling adults (mean age 74.3[SD 6.3] years, 54.8% female) using a modified FRAIL scale and modified FP. Mortality was matched to death records. RESULTS: The FRAIL scale demonstrated significant predictive validity for mortality up to 10 years (Frail adjHR: 2.60, P < .001). DTA findings were acceptable for specificity (86.8%) and Youden index (0.50), but not sensitivity (63.6%), or area under the receiver operator curve (auROC) (0.75). DTA estimates were more acceptable when a cut-point of ≥2 characteristics was used rather than ≥3 in the primary DTA analysis. CONCLUSION: The FRAIL scale is a valid predictor of mortality. DTA estimates depend on FRAIL scale cut-point used. This instrument is a potentially useful frailty screening tool. |
Keywords: | Australia frailty mortality screening |
Rights: | © 2020 AJA Inc. |
DOI: | 10.1111/ajag.12829 |
Published version: | http://dx.doi.org/10.1111/ajag.12829 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
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