Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/114017
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Type: | Journal article |
Title: | High-sensitivity Sagnac-interferometer biosensor based on exposed core microstructured optical fiber |
Author: | Li, X. Nguyen, L.V. Zhao, Y. Ebendorff-Heidepriem, H. Warren-Smith, S.C. |
Citation: | Sensors and Actuators B: Chemical: international journal devoted to research and development of physical and chemical transducers, 2018; 269:103-109 |
Publisher: | Elsevier |
Issue Date: | 2018 |
ISSN: | 0925-4005 0925-4005 |
Statement of Responsibility: | Xuegang Li, Linh V. Nguyen, Yong Zhao, Heike Ebendorff-Heidepriem, Stephen C. Warren-Smith |
Abstract: | A novel, high sensitivity Sagnac-interferometer biosensor based on exposed core microstructured optical fiber (ECF) has been designed and implemented in this paper. The exposed core fiber has noncircular symmetry and thus exhibits birefringence and can form a sensing element within a Sagnac loop interferometer. The exposed-core fiber design provides direct access to the evanescent field, allowing the measurement of bulk refractive index (RI) with a sensitivity of up to −3137 nm/RIU while maintaining the fiber’s robustness. The sensor can also detect the localized refractive index changes at the fiber core’s surface as the result of a biological binding event. We demonstrate the use of this sensor for label-free sensing of biological molecules by immobilizing biotin onto the fiber core as the probe to capture the target molecule streptavidin. |
Keywords: | Biosensor; Sagnac-interferometer; Refractive index measurement; Exposed-core microstructured optical fiber |
Rights: | © 2018 Elsevier B.V. All rights reserved. |
DOI: | 10.1016/j.snb.2018.04.165 |
Published version: | http://dx.doi.org/10.1016/j.snb.2018.04.165 |
Appears in Collections: | Aurora harvest 3 Physics publications |
Files in This Item:
File | Description | Size | Format | |
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hdl_114017.pdf | Accepted version | 2.2 MB | Adobe PDF | View/Open |
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