Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/131080
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Exploiting conformationally gated electron transfer in self-assembled azobenzene-containing cyclic peptides using light |
Author: | Horsley, J.R. Wang, X. Yu, J. Abell, A.D. |
Citation: | Electrochimica Acta, 2021; 381:138232-1-138232-8 |
Publisher: | Elsevier |
Issue Date: | 2021 |
ISSN: | 0013-4686 1873-3859 |
Statement of Responsibility: | John R.Horsley, Xiaobo Wang Jingxian Yu, Andrew D.Abell |
Abstract: | An azobenzene photoswitch was incorporated into a peptide as a side chain constraint to allow interconversion between two photostationary states (PSS) comprising well-defined β-strand geometry. The peptide was covalently attached to a carbon electrode with a terminal redox-active ferrocene moiety for electrochemical interrogation of each PSS. While readily switching in solution, the increased molar volume of the cis isomer is believed to hinder the conformational change in the peptide on a self-assembled monolayer (SAM). The introduction of diluents to increase the distance between chromophores reduced these steric effects to provide on/off switching between the two photostationary states of the peptide on the SAM using alternative irradiation of UV and visible light. The structural and electronic properties of each PSS differed significantly, enabling this gated approach to exploit changes in the molecular structure that provide opportunities for the design and development of future photoswitchable peptide-based SAMs with controllable electronic functions, for applications in areas such as sensing and molecular electronics. |
Keywords: | Electron transfer; photoswitchable peptides; conformational gating; β-strand; steric hindrance |
Rights: | © 2021 Elsevier Ltd. All rights reserved. |
DOI: | 10.1016/j.electacta.2021.138232 |
Grant ID: | http://purl.org/au-research/grants/arc/CE140100003 http://purl.org/au-research/grants/arc/DP180101581 |
Published version: | http://dx.doi.org/10.1016/j.electacta.2021.138232 |
Appears in Collections: | Aurora harvest 8 Chemistry publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.